Zidovir 100mg (Zidovudine)
Zidovudine (Zidovudine 100mg) is used in combination with other antiretroviral (ART) medicines for the treatment of human immunodeficiency virus (HIV-1) infection. Zidovudine is also indicated for use in HIV-positive pregnant (over 14 weeks) women for prevention of maternal-fetal HIV transmission (passing of infection), and for primary preventive treatment of HIV infection in new-born infants.
How Dose Zidovir 100 mg work?
Zidovudine belongs to a group of medications called nucleoside analogue reverse transcriptase inhibitors (NRTIs), also known as antiretrovirals. Zidovudine does not cure HIV infection; it reduces the amount of viruses in the body by inhibiting the enzyme (viral reverse transcriptase) which is essential for the virus to grow. Further, zidovudine also increases some white blood cells (CD4 cells) of the body that are important in fighting infections.
What is Zidovudine?
Zidovudine (Zidovudine 100mg), also sold under the brands Retrovir and Zidovir among several other trade names, is an antiviral drug. This medication belongs to a group of HIV medicines called reverse transcriptase inhibitors that prevent the HIV virus from reproducing in the body. Zidovudine is prescribed for the treatment of HIV that causes the disease called acquired immunodeficiency syndrome or AIDS. However, this medication will not cure the body of HIV or AIDS. This medication may also be given for conditions not mentioned here.
Important Information about Zidovudine
Do not take Zidovudine antiviral HIV medicine (Retrovir, Zidovir) if you have a known allergy to it or any medicine that has Zidovudine. Also do not take Zidovudine with other medicines that also contain Zidovudine or Stavudine. Lactic acidosis has been observed in some people who took Zidovudine. Initial symptoms of lactic acidosis may deteriorate over time and can prove fatal. Hence you must get medical attention right away on first signs of lactic acidosis such as muscle pain or weakness, numb or cold feeling in the limbs, breathing trouble, stomach pain, or nausea with vomiting. Zidovudine can also cause severe and life threatening damage to your liver. Let your doctor know in advance if you have a condition affecting liver, especially Hepatitis C. Seek medical attention right away if you have any of the following symptoms of liver damage: sever pain in upper stomach which advances to the back, nausea and vomiting, fast heartbeats, itching, loss of appetite, dark urine, clay colored stools, or jaundice. Zidovudine can lower the count of white blood cells, the component of blood that helps the body to fight infections. You must take necessary precautions to avoid getting infected such as not being near sick people or avoiding activities that increases the risk of bleeding. Let your doctor know right away if you get any signs of an infection while taking this medication. Lamivudine is an FDA pregnancy category C drug. It is not known if it can harm an unborn baby if taken while being pregnant. HIV can be transmitted to your baby if you are not treated properly during pregnancy.
Before taking Zidovudine
Before taking Zidovudine (Zidovudine 100mg) antiviral HIV medicine, take care of all precautions mentioned above. Discuss them with your doctor and clear all doubts which you may have about this drug. To be sure that Zidovudine is safe for you, inform your doctor in advance if you have any of the following conditions: kidney disease, bone marrow suppression, anemia, an active infection, or if you have used other HIV drugs in the past.
How to take Zidovudine?
Take Zidovudine HIV/AIDS medication (Retrovir, Zidovir) strictly according to your doctor?s direction or according to the instructions on the medication label. Do not alter the dosage unless your doctor advises you to do so. Also, do not take this medication after the prescribed period is over. All medications come with a patient leaflet. Refer the instructions in them for detailed information on that particular medication. HIV/AIDS is usually treated with a combination of drugs. Always take the prescribed drugs as directed by your doctor. Store this medication in a cool and dry place. Always store Zidovudine in a cool and dry place.
Things and Activities to avoid while taking Zidovudine
Zidovudine can lower the count of white blood cells, the component of blood that helps the body to fight infections. You must take necessary precautions to avoid getting infected such as not being near sick people or avoiding activities that increases the risk of bleeding. Let your doctor know right away if you get any signs of an infection while taking this medication. Zidovudine will not help your body get rid of HIV/AIDS. It will stop the growth and multiplication of the virus. Chances of spreading the HIV will still remain the same through unprotected s**, infected razors or toothbrush. Hence, avoid these activities and things. Also avoid alcohol as alcohol can increase the chances of liver damage.
What if I miss a dose?
If you miss a dose of Zidovudine, take it as soon as you remember. Don?t take the missed dose if the time to take the next dose is almost up. Taking multiple doses near to each other can lead to excess medication in your body which can be harmful.
What if I overdose?
In case of an overdose of Zidovudine, get emergency medical attention or call the Doctor immediately. Overdose can cause some of the side effects listed below in this guide.
Zidovudine Side Effects
Some common side effects of Zidovudine are:
If any of these effects persist or deteriorate, seek medical attention right away. Some people may experience a deteriorating of a previous medical condition as their immune system recovers, or develop new conditions due to overactive immune system. Let your doctor know right away if you develop any new condition or any of you existing conditions worsen. The side effects mentioned above are not the only ones that you may experience or witness due to Zidovudine. If you get any serious side effects due to this medication, contact your doctor right away.
Zidovudine Dosing Information
Zidovudine dosage may depend on a range of factors like age, s**, drug allergies, or seriousness of the condition among several other factors. Your dosage will be determined by your doctor after examining you properly. Remember to follow your doctor?s advice properly for best results.
Q: Is zidovudine an antibiotic?
A: No, zidovudine is not an antibiotic; it belongs to a class of drugs called antiretrovirals.
Q: Is zidovudine a prodrug?
A: Yes, zidovudine is a prodrug and must be activated (by phosphorylation in lymphocytes) in the body to exert its antiviral action.
Q: Is zidovudine a protease inhibitor?
A: No, zidovudine is not a protease inhibitor; it is a nucleoside analogue reverse transcriptase inhibitor.
Q: Does zidovudine cross placenta?
A: Zidovudine crosses placenta and thereby reducing the HIV transmission from the mother to the fetus.
Q: How much does zidovudine cost?
A: The price of zidovudine may vary depending upon the brand prescribed to you. Please read the instruction on the package for the correct price of the product.
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